Hi, I was dx with AML last october, Inv 16 FLT3, i had induction then three rounds of consolidation. I just started my first round of maintenance chemo, which is the dacogen. I was wondering if anyone else was on this protocol, Its day 14 for me, my platelets have dropped to 44, but my hemoglobin is staying up, and my white count is normal. I was wondering if this is the case for anyone else? I know the chemo is working its course and what not, I just think its curious that my platelets are the only thing dropping, my doctor said its nothing to worry about, and i'm not worried, just curious ![]()
Decitabine can cause myelosupression, but there are many variables. I'd rely on the opinion of your doctors who have your complete counts and history. I assume they've recommended a maintenance trial due to FLT3. Are you being followed routinely with PCR assays?
Are you on other meds, possibly an anti-depressant? I only mention this because I was on an anti-depressant (Remeron) briefly after transplant, and it made my platelet count steadily plummet. I went off it due to the migraines it caused, and my platelet count climbed back up. Later the psych doc told me, yeah, that's a side effect. So I'm just saying, consider all meds you may be taking. Otherwise, I'd rely on your doctor's wisdom, they see count patterns all the time, and if they aren't worried, that's a good thing. Good luck with the maintenence!
Are you m3 (APL)?
Sorry, I have no memory.
I was dx'd last November with same. I start round 4 of maintenance tomorrow along with another bmb. ughhhhh. Except for the punching bag effect, I'm doing well. Would love to hear how you are. My platlets dropped low after round 1 also but now everything drops and takes long to recover. They've reduced me to 4 day and I'm hopping as of tomorrow it's down to 3 days. It took 6 weeks for my counts to recover after round 3. How about you?