The Leukemia & Lymphoma Society - Fighting Blood Cancers
21 Replies Last post: Feb 25, 2010 8:22 PM by L.Christmas   Go to original post 1 2 Previous Next
FYE   88 posts since
Jun 15, 2009
Currently Being Moderated
15. Nov 3, 2009 10:31 AM in response to: Denise
Re: Big Decision

This is great. It is much easier when the all agree.

L.Christmas   7 posts since
Feb 3, 2010
Currently Being Moderated
17. Feb 3, 2010 3:55 PM in response to: Denise
Re: Big Decision

I was diagnosed with mixed HL 2a in 2007 and faced a similar decision

 

I am also a physician, and evaluated the data on the subject -

 

Ultimately, I decided to take 1 month of radiation in addition to 4 cycles of ABVD for one main reason- mostly because I did not want to look back and wish I had taken the radiation since I knew recurrence rate was slighly lower with this route

 

 

1. prognosis after PET remission after 2 cycles is excellent, so this would suggest ABVD only

2. disease free occurrence is 95 vs 88% after 5 years if you take the ABVD + radiation route, this suggest ABVD + involved field radiation

3. what you need to weigh this against is the risk of involved field radiation for secondary malignancies 20 years down the road - the truth is that studies for secondary malignancies were done with mantle radiation, so there is no way to truly compare

4. also consider if you are a woman the risk of breast cancer with radiation (secondary malignancy)

5. also consider if the disease is right sided or left sided - left sided radiation may increase risk of heart disease

L.Christmas   7 posts since
Feb 3, 2010
Currently Being Moderated
19. Feb 23, 2010 9:29 PM in response to: Denise
Re: Big Decision

Denise,

 

I have had no leftover effects. I had Bleomycin toxicity and stopped Bleo after 2 cycles as well. I do not feel short of breath. The fatigue improved about a year after treatment was completed. (wow it seemed forever)

 

This fall I completed my 1st 5K run, and I'll be trying the broad street run in Philly in the spring(10miles)

 

I hope all goes well with your lung issue. The bronchoscopy is considered a far less invasive way to evaluate if you have an active issue. It may takes weeks however before fungal culture results return.

 

Let me know if I can help you.

 

 

Anthony

L.Christmas   7 posts since
Feb 3, 2010
Currently Being Moderated
21. Feb 25, 2010 8:22 PM in response to: Denise
Re: Big Decision

Denise,

 

 

Good luck with the bronchoscpy results. I know that waiting is a significant part of the stress you are having.

 

Soon enough you will be feeling well enough to do more for yourself and others.

 

Anthony

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