My mother was diagnosed with essential thrombocytosis which she had for about 12 years when suddenly at the age of 52 she was diagnosed with myelofibrosis.  I say suddenly as she lived pretty event free before this, taking the occassional warfarin.  By the time the myelofibrosis was discovered it was found that she was most likely in a stage where the disease was progressing to AML.  Unfortunately she passed away one month later due to chemo complications.  Her bone marrow was totally "dry".  I do recall though, that her doctor had told her that this all may have been caused by Prozac  and that in very rare cases, the bone marrow may be affected(this was 15 years ago)  All these years I never wanted to delve into her conditions for fear of discovering more than I want.  That all changed two years ago when my own four year old son was diagnosed with t-cell ALL.  Of course the doctors claim that there is absolutely no connection, just coincidence, as they are two different disorders.  Once I had researched the side effects of prozac and did find that it regulates seratonin through some sort of platelet connection.  We always wondered after this conversation with the doctor if the prozac did indeed affect my mother's bone marrow production in some rare way.

Just curious to know if anyone with MDS was ever on any medications before their diagnosis, as to hear from real people is much more reliable sometimes than reading controlled studies in medical journals.   Thanks