The Leukemia & Lymphoma Society - Fighting Blood Cancers
4 Replies Latest reply: Jun 2, 2012 8:43 AM by ChrisC RSS

High Initial WBC Count -Collateral long term Damage

Johnc Registered Users
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Does anyone know if there is collateral damage to one's system by starting CML with higher WBCs than lower ones?

 

Johnc

  • Re: High Initial WBC Count -Collateral long term Damage
    CallMeLucky Registered Users
    Currently Being Moderated

    Just based on the white count alone, no.  The counts are not as important as the phase of the disease and the quality of the bone marrow.

  • Re: High Initial WBC Count -Collateral long term Damage
    threedprof Registered Users
    Currently Being Moderated

    I suppose you can say there can be damage with high WBC counts.  As some have pointed out, once their levels return to normal the damage seems to heal and reverse.  At the start, my counts were in the 360K+ range with 1.2 Mil Platelets.  My vision turned green in the morning and lasted longer and longer.  Then I developed a permanent tiny blind spot in my right eye.  The green tint to my vision has long repaired itself and my elevated createnine levels have finally dropped into normal range now that i'm no longer taking Gleevec.

  • Re: High Initial WBC Count -Collateral long term Damage
    ChrisC Registered Users
    Currently Being Moderated

    Possibly some permanent hearing loss from high WBC (459k) and/or from Gleevec, not sure which, it was very noticeable by a couple of months after dx. I did some online searching and found a couple of similar cases of sudden hearing loss soon after starting G, but with higher WBC (600–700k), and also that Gleevec was being checked out by the FDA due to the number of reports re hearing loss. We may never know all the consequences due to the high WBC, since we may not associate cause and eventual effect.

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