I find many people write that Hydroxyurea, a TKI or both were used to bring down their high PLT at dx. I have not heard anyone mention they were given blood thinners. I was given Wafarin along with Hydroxyurea. As my PLT were 600,000 at dx, it really knocked them down very fast. Sadly they have not made a comeback.
Was anyone else given a blood thinner at dx?
Not I, but my platelets were in normal range. In fact, since they initially thought I might be bleeding internally (from APML), I don't think they would have given me a blood thinner. They told me to get off the ibuprofen because of all the crazy bruising. So I'm on the opposite side of the spectrum, I guess.
My platelets were over 2 million at diagnoses. The only reason I went on Hydroxreau was because I had an appointment to see an onc about a clinical trial of 400mg vs 800mg of Gleevec. To be in the study you couldn’t have been on a TKI, thus the Hydroxreau. I decided I didn’t want to do the study for various reasons.
Hind site, I wish I had never went on Hydroxyurea. I think I took something like 3 x the normal dose as the platelets weren’t coming down. Also I felt like I had an elephant on my chest and had a hard time breathing.
I think that Gleevec would have taken care of the platelets with out any other drugs.